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Highlights
Drs. Green and Felsenfeld discuss the project in this video interview
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10K Genomes Project to Create Vertebrate Genome Zoo

As DNA sequencing costs decline, a group of research biologists has pondered reading evolution's notebooks in the genomes of thousands of vertebrate species. Using a workshop to organize their ideas, the group has proposed The 10K Genomes Project in a paper published Nov. 5 in the Journal of Heredity. Co-authors include NHGRI's Eric Green M.D., Ph.D. and Adam Felsenfeld, Ph.D.

Read the paper: Genome 10K: A Proposal to Obtain Whole-Genome Sequence for 10,000 Vertebrate SpeciesPDF file
Read the UCSC press release: Scientists propose a "genome zoo" of 10,000 vertebrate species
NHGRI-supported researchers have sequenced the equine genome using DNA from Twilight, a Thoroughbred mare from Cornell University in Ithaca, N.Y. Courtesy:Doug Antczak, Cornell University

Hay! First Analysis of Horse Genome

An international research team, supported in part by NHGRI, has found that the genome of the domestic horse, Equus caballus, has a structure remarkably similar to our own genome. Published in the Nov. 6 issue of Science, the team's landmark analysis also sheds new light on centromere evolution.
Read the Science article
Horse genome sequence and analysis published in Science
From NHGRI's Talking Glossary of Genetic Terms: Centromeres
3-D cell illustration

New and Improved! The Talking Glossary of Genetic Terms

Listen to researchers explain more than 200 terms related to genetics and genomics. View more than 100 color illustrations and 3-D animations. Test your knowledge of genetics in two online quizzes. To reach this educational resource designed for learners at all levels, go to www.genome.gov/glossary

The National Human Genome Research Institute led the Human Genome Project for the National Institutes of Health, which culminated in the completion of the full human genome sequence in April 2003. Now, NHGRI moves forward into the genomic era with research aimed at improving human health and fighting disease.

bullet The Large-Scale Genome Sequencing Program
bullet Clinical Research
bullet The Ethical, Legal and Social Implications (ELSI) Research Program
bullet The Office of Population Genomics




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Read the story behind the Human Genome Project

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Towards a Molecular Understanding of Melanoma Metastasis
Rhoda Alani, M.D.
November 19, 2009

Evolutionary conserved pathways suppress genomic instability
Kyungjae Myung, Ph.D.
November 20, 2009

DIR Seminar Series
Job Dekker, Ph.D.
December 3, 2009

DIR Seminar Series
Didier Stainier, Ph.D.
December 17, 2009