DIR Projects

Database of Mutations Causing Human X-Linked SCID

X-linked severe combined immunodeficiency (XSCID or X-SCID) is an immune disorder caused by mutations in the X-linked gene IL2RG, which encodes the common gamma chain (c) of the lymphocyte receptors for interleukin-2 (IL-2) and many other cytokines. A database of human XSCID mutations (IL2RGbase) has been assembled. Information on new mutations may be submitted online.

  IL2RGbase: Database of Mutations Causing Human X-Linked SCID

  Distribution of IL2RG mutations causing X-SCID

  Literature citations for the references listed in the mutation data tables

  IL2RGbase data submission form

  1997 X-Linked SCID Workshop

  Research on X-Linked SCID at NHGRI

  List of Investigators

  Other Resources